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Herb-Drug Interactions Can Lead to Severe Adverse Reactions - Diana Ernst, RPh Herbals can affect the pharmacokinetic and pharmacodynamic properties of prescribed medicines A new study published in the British Journal of Clinical Pharmacology highlights the importance of increasing patient awareness regarding the possible adverse consequences of herb-drug interactions (HDI)....Continue reading

Is Peppermint Oil an Effective Treatment for Irritable Bowel Syndrome? Cassandra Pardini, PharmD February 22, 2019 Peppermint oil possesses several properties that are relevant in the treatment of IBS ... Peppermint oil (PO) was found to be safe and effective in treating pain and global symptoms associated with irritable bowel syndrome (IBS) in adult patients, according to the results of a recently published systematic review and meta-analysis. In order to evaluate the effect of PO in the treatment of IBS, the authors reviewed abstracts of randomized controlled trials that compared enteric-coated PO to placebo in adult patients with IBS, diagnosed using Manning or Rome I, II, III, IV diagnostic criteria. Eligible studies were appraised using the Cochrane risk of bias tool. The primary outcomes included the proportion of patients with global symptom improvement and improved abdominal pain. Twelve studies, with a total of 835 patients, met inclusion criteria and underwent systematic review and data analysis. The study authors reported, For global symptom improvement, the risk ratio (RR) from 7 RCTs for the effect of PO (N=253) vs placebo (N=254) on global symptoms was 2.39 [95% confidence interval (CI): 1.93 to 2.97], I2=0%, z=7.93 (P<.00001). When assessing abdominal pain from 6 RCTs, the risk ratio for the effect of PO (N=278) compared with placebo (N=278) was reported as 1.78 (95% CI: 1.43, 2.20), I2=0%, z=5.23 (P<.00001). The number needed to treat with PO to prevent 1 patient from having persistent symptoms was 3 for global symptoms and 4 for abdominal pain, the study authors added. Results of the study also found PO to be relatively safe. Data analysis of 8 RCTs found that 9.3% of PO patients reported adverse effects (32 events, 344 total) compared with 6.1% of placebo patients (20 events, 327 total) (RR: 1.40; 95% CI: 0.87 to 2.26; I2=0%, z=1.39; P=.16). Related Articles Pregabalin Evaluated in Patients With Irritable Bowel Syndrome Hypnotherapy vs Education for Relief of IBS Symptoms Irritable Bowel Syndrome Treatments The strength of our findings is reflected by the large effect size of PO over placebo in the improvement of abdominal pain and global symptoms and by the low heterogeneity across included studies, the authors concluded. Reference Alammar N, Wang L, Saberi B, Nanavati J, Holtmann G, Shinohara RT, Mullin GE. The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data. BMC Complementary and Alternative Medicine, 2019. DOI: doi.org/10.1186/s12906-018-2409-0. https://www.empr.com//is-peppermint-oil-an-effective-trea/

Screen Time Linked to Poorer Child Developmental Performance More screen time tied to poorer performance on developmental screening tests at 36, 60 months. HealthDay News Screen time is associated with poorer performance on developmental screening tests among young children, according to a study published online January 28 in JAMA Pediatrics.... Sheri Madigan, PhD, from the University of Calgary in Alberta, Canada, and colleagues examined the directional association between screen time and child development in a three-wave cross-lagged panel model. Data were included for 2441 mothers and children and were available when children were aged 24, 36, and 60 months. Developmental outcomes were assessed via maternal report using the Ages and Stages Questionnaire, Third Edition. The researchers observed significant correlations for higher levels of screen time at ages 24 and 36 months with poorer performance on developmental screening tests at 36 and 60 months, respectively (, 0.08 and 0.06, respectively). An association between lower scores on developmental screening tests and higher levels of screen time at later time points was not observed. Related Articles American Heart Association Urges Screen Time Limits for Youth Alcohol Exposure Via Breastmilk May Affect Infant Development To our knowledge, the present study is the first to provide evidence of a directional association between screen time and poor performance on development screening tests among very young children, the authors write. Understanding the directional association between screen time and its correlates, and taking family-based steps to engage with technology in positive ways may be fundamental to ensuring developmental success of children growing up in a digital age. Abstract/Full Text https://www.empr.com//screen-time-linked-to-poorer-child-/

CDC: Increases in Yoga, Meditation for Children in 2012-2017 Among adults, increases seen in use of yoga, meditation, chiropractor during same time period. HealthDay News The use of yoga and meditation have increased in recent years among children and adults, while use of chiropractors has also increased among adults, according to two November data briefs published by the US Centers for Disease Control and Prevention National Center for Health Statistics.... Lindsey I. Black, MPH, from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from the National Health Interview Survey 2012 and 2017 to examine use of yoga, meditation, and chiropractors among children aged 4 to 17 years. The researchers found that from 2012 to 2017, there was an increase in the use of yoga (from 3.1 to 8.4%) and meditation (from 0.6 to 5.4%) during the previous 12 months. In 2017, girls were more likely than boys to have used yoga in the previous 12 months; older children (aged 12 to 17 years) were more likely than younger children (4 to 11 years) to have used meditation and a chiropractor in the previous 12 months. Related Articles Heat Not Needed for Bikram Yoga to Confer Vascular Benefits AUA: Yoga Can Reduce Urinary Incontinence in Older Women Yoga Found to Alter Gene Expression for the Better Tainya C. Clarke, PhD, MPH, also from the National Center for Health Statistics, and colleagues examined adults’ use of yoga, meditation, and chiropractors in 2012 and 2017 using data from the National Health Interview Survey. The researchers found that from 2012 to 2017, there were increases in the use of yoga (from 9.5 to 14.3%), meditation (from 4.1 to 14.2%), and chiropractors (from 9.1 to 10.3%) during the previous 12 months. In 2012 and 2017, yoga was the most commonly used complementary health approach. In 2017, women were more likely than men to have used yoga, meditation, and chiropractors in the previous 12 months. In recent years, the practice of yoga and meditation has become more mainstream, Clarke and colleagues write. Abstract/Full Text Black Abstract/Full Text Clark https://www.empr.com//cdc-increases-in-yoga-meditation-fo/