Pike Lab

Check out some of the work, published this summer, from Dr. Alexandra Moser's graduate thesis. In this study we explored the combined effects of the Alzheimer's risk gene, APOE4, and obesity using a mouse model of Alzheimer's disease. We find that Alzheimer's pathology and neuroinflammation are increased in APOE4 mice fed a Western diet.

Check out some of the work, published this summer, from Dr. Alexandra Moser's graduate thesis. In this study we explored the combined effects of the Alzheimer's risk gene, APOE4, and obesity using a mouse model of Alzheimer's disease. We find that Alzheimer's pathology and neuroinflammation are increased in APOE4 mice fed a Western diet.

Congratulations to Dr. Alexandra Moser! We are all so proud that you successfully defended your PhD work yesterday. You've accomplished so much and we are excited to see the great things you'll do in the future!

Congratulations to Daniella Lent-Schochet, a long time Pike Lab undergraduate researcher who will be honored at graduation next week as a USC Discovery Scholar! "The Discovery Scholars Program honors students who excel in the classroom while demonstrating the ability to create exceptional new scholarship or artistic works." Congrats on a well-deserved honor.

Congratulations Christian! This week the Pike lab boss received the USC Mellon Mentoring Award for Mentoring Graduate Students. The award really recognizes the remarkable current and former Pike lab graduate students, who continue to excel in life both within and outside the world of science.

Congratulations to Pike lab undergraduate researcher Amanda Zhou! She was awarded a Rose Hills Summer Research Fellowship. This incredible program generously supported by the Rose Hills Foundation provides the undergraduate researcher with a $5000 stipend with another $1000 for the sponsoring laboratory. Amanda will be working with graduate student Alexandra Moser investigating how Alzheimer’s disease risk is affected by the interaction between obesity, aging, and testosterone loss. Thank you Rose Hills Foundation.

Congratulations to Pike lab postdoc Amy Christensen and grad student Alexandra Moser. Amy's poster presentation at the ENDO 2015 conference in San Diego received the prestigious Presidential Poster Competition Award! Alexandra was the recipient of the Early Career Forum Travel Award for the 2015 ENDO conference. Great job ladies.

Our beautiful non-denominational holiday plant!

Pike Lab published a paper in Journal of Neuroinflammation this week. Our research shows that low testosterone and obesity in male mice combine to increase neuroinflammation and worsen neural health. Bottom line for middle-aged men: lose weight and/or take testosterone!

Welcome to new Pike Lab postdoctoral scientist Aaron Barnett.

Check out our latest review of Alzheimer's and diabetes!

The year is young and the Pike lab already has its second paper published! We find that a novel SARM is able to promote neuroprotection in vitro and in vivo.

Starting the new year off right! Check out that latest paper from Pike lab reporting the effects of progestagens on neuron survival.

Congratulations to Pike Lab undergraduate research assistant Daniella Lent who got married last weekend to Avi Schochet!