MTHFRDoctor

Are you struggling with Thyroid Disease? Many of our patients are suffering from autoimmune thyroiditis or from subclinical hypothyroidism and their doctors report their labs are normal. Caution! Is your doctor ordering a complete thyroid panel: TSH, total T4, Free T4, Total T3, Free T3, reverse T3(blocker hormone), TPO antibodies and thyroglobulin antibodies. Thyroid disease is highly related to Estrogen Dominance, Celiac Disease and Gluten intolerance, poor detoxification ...from BPA found in plastics, low Iodide levels, high Chlorine,Fluoride, or Bromide exposure found abundantly in our drinking water. What should you consider doing? 1. Order a total Estrogen level and Estrone sulfate with your blood panel. Use Estrofactors and MetaI3C by Metagenics to pull the estrogen down and free up your thyroid. Also add 2 minerals Molybdenum 600mcg 2 x a day and Manganese 10mg a day to pull estrone sulfate down. You should take METHYLCARE by Metagenics to increase methylation as well 2. Add Metagenics Thyrolar which contains all the thyroid stimulation and Rhodiola to block the over production of Reverse T3. 3. Gluten Dairy Free diet 4. Interval fasting means no food until 12pm to 6pm. No cheating and follow the paleoketo diet by Dr. Fong author of the The Obesity Code 5. Don’t use artificial sweeteners especially avoid Splenda and aspartame 6. Increase daily detox by drinking Metagenics UltraClear Renew 2x a day and take with Advaclear 2 x a day 7. Sweat in the sauna or hot yoga! 8. Drink Aqua Hydrate alkaline water found in most grocery stores .... between meals not with a meal. 9. Take a powerful Probiotics/prebiotic such as Ultraflora Synergy by Metagenics or ProbiomaxDf Sb by Xymogen. Probiotics MUST TOUCH YOUR TONGUE so open and put in applesauce or a beverage 10. Take high quality Omega 3s like Metagenics Omegagenics not Costco FISH OIL! You take pure omega 3s only! 11. If you want to lose weight you MUST walk on a treadmill or outside for no less than an hour a day to burn your stored sugar in the liver and then start to burn Fat. Your exercise needs to be moderate intensity meaning you can speak but it feels difficult to carry on a conversation. Good Luck! Your MTHFRdoctor Metagenics is available on-line access code: BRIGGSMD should give you access to my physician discount! Enjoy

Are Phenols Making You Sick? http://wp.me/p5xNmW-V

If Fibromyalgia Related to Sulfites? In clinic we are seeing a growing patient population with fibromyalgia and chronic fatigue. Fibromyalgia is characterized by a number of point areas of muscle tenderness throughout the body. Through genomic results, it has become apparent that many of these patients have an up-driven trans-sulfuration pathway in the body. That means that in many patients when the body lacks the ability to use folate in its fullest, the body will rely mo...re heavily on a secondary pathway called the trans-sulfuration pathway. This pathway, while processing sulfur-containing amino acids, can lead to an excessive production of sulfites. Sulfites naturally lead to an excessive production of acidic cofactors, increasing an acidic burden on the body and depleting the body of essential minerals such as molybdenum, manganese, magnesium, and many other critical minerals. Many of our fibromyalgia patients find great relief of their muscle pain and body aches when we place them on a multivitamin/mineral such as Mitofuel, which contains methylated B vitamins and higher dosages of critical minerals and anti-oxidants. We also often use strong alkalinizing approaches such as can be achieved by drinking alkaline mineral waters, such as Aquahydrate or alkalinizing medical foods such as UltraClear Renew by Metagenics in combination with Sulfite XX which is simply an extra dosage of molybdenum and manganese- chelated minerals at two meals of the day. This approach appears to help clear sulfites more quickly while helping to better produce healthier sulfates used by the liver for Phase II detoxification. Could it be that fibromyalgia is a syndrome of excess sulfites, an acidic burden, and impaired detoxification? To date, there is no known single gene related to the development of fibromyalgia, but we do see common hereditary links in our patient population. Please visit EpigeneticsRX.com for further information about nutrient support. Bridget Briggs, M.D

A lot of doctors and clinicians believe that this is old news. Yah, Yah they say.... all you have to do is just give people with the MTHFR mutation methylfolate right. I mean how hard can this be? Well, I can tell you as an experienced clinician..... blindly prescribing methylfolate such as in the rx Metanx made a lot of people sick. I literally saw people take massive dosages of methylfolate and methylB12 develop a whole hose of other problems. The methylfolate cycle is... connected to a number of other cycles in the body such as the urea cycle, the biopterin cycle, and the tran-sulfuration cycle. I watched people over ingest methyl groups which caused joint pain, tendinitis, bursitis, Small intestinal bacterial overgrowth, heart burn, allergies, itchy skin....all of these side effects were a result of the over production of sulfites in the body via the up-regulation of the transulfuration pathway. In essence, when certain individuals over consume too much methylfolate they can increase the production of sulfur containing metabolites and amino acids in the body. Sulfur is important in protein structural support and has a tendency to make proteins spin or turn. This includes keratin protein which in found in hair and nails. Therefore, I have seen patients over-methylate and therefore develop longitudinal lines in their nails and create waves or curls in the hair, or increase sulfur containing hormones in their blood such as estrone sulfate or DHEAsulfate. Whereas curly hair has never made people sick, but the same can occur to tendons and fascia creating plantar fasciitis, tendonitis, or bursitis. Many people who complain of fibromyalgia type of pain or joint pain are actually experiencing an excess of sulfites in the body and would benefit from taking Sulfite XX twice a day. This mineral cocktail helps people clear sulfites and produce healthy sulfates. Sulfites are pro-inflammatory and toxic as compared to sulfates which are critical to joint and tendon strength and critical for phase II liver detoxification. Sulfates support a healthy Gut barrier and Blood brain barrier, as well as bronchial and vascular dilation. This is why we treat bronchial constriction such as seen in asthma with albuteral sulfate and this is why we can treat joint and muscle pain with magnesium sulfate found in Epsom Salt baths. See more

The enzyme MTHFR, also known as methylene tetrahydrofolate reductase, is the critical enzyme in the human body essential for the activation of folate to the methylated form of folate called L-5MTHF. This L-5MTHF is critical in several biochemical steps involved in human metabolism. It is critical in detoxification, hormone balance, tumor or cancer prevention, cell growth, and neurotransmitter synthesis. The enzyme mutation known as MTHFR C677T or MTHFR A1298C can be found ...in up to 40% of Americans, although it is found worldwide. This simple enzyme defect can be easily treated with a special form of folic acid called methyl folate. Millions of Americans who suffer from chronic disease, mental disorders, and hormone imbalance are seeing positive life changes after the simple ingestion of the correct form of folate. Ask your doctor to test you for the MTHFR genetic mutation