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Locality: Burbank, California

Phone: +1 818-669-0490



Address: 817 N Valley St 91505 Burbank, CA, US

Website: hollywoodkangen.com

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Kangen Water Burbank 12.11.2020

The amazing Rhonda Patrick has a new podcast out on the subject of anti aging. Here is a quote from her announcement. I found this really interesting because sh...e has long been a proponent of hormetic heat stress (20 - 30 minutes in a sauna over 163 degrees.) She has a great pdf for download on her site FoundMyFitness.com detailing how sauna use helps prevent inflammation and cognitive decline along with many other benefits. Protein Aggregation, Iron Overload & the Search for Longevity Compounds with Dr. Gordon Lithgow [VIDEO] Gordon Lithgow, Ph.D. on Protein Aggregation, Iron Overload & the Search for Longevity Compounds Share Video: Facebook Twitter Google+ The podcast I share with you today features Dr. Gordon Lithgow, a professor of gerontology at the Buck Institute for Research on Aging. Gordon studies mechanisms of aging by identifying compounds that extend lifespan or prevent age-related disease. He has discovered a range of factors that can lengthen life in the microscopic worm Caenorhabditis elegans or C. elegans as they are known, and he applies these findings to studies in human cell cultures. Now, you may ask yourself, what do I have in common with something like a tiny nematode worm? And the answer to that is gene homology! In fact, about 35% of the genes possessed by C. elegans have human homologs, which means that a version is also found in humans. The beauty of a model like C. elegans in aging research, as you will learn in this conversation with Dr. Gordon Lithgow, is that these animals have a very short lifespan. That means that, in comparison to more long-lived higher order organisms like rodents, it's a bit more straightforward to change up the conditions and see what happens to their lifespans! You can do this more quickly and more cheaply. By way of example, you might try adding in something like even a small amount of environmental stress, which, if we're talking about heat stress, actually was shown to increase lifespan in worms when used in the right dose a discovery that, as we'll also discuss, Dr. Gordon Lithgow, today's guest, actually made in the course of his research back in 1995. But, it's also practically useful for determining if certain compounds, including vitamins and minerals, may be candidates for increasing lifespan as well. This is where the Caenorhabditis Intervention Testing Program comes in. The Caenorhabditis Intervention Testing Program, which Dr. Gordon Lithgow is the director of, is a multi-institution effort, sponsored by the National Institute on Aging, a division of the NIH, designed to screen bioactive compounds for their ability to extend lifespan and enhance health using nematodes as a model system for potential effects. The Caenorhabditis Intervention Testing Program is actually a spin-off of another program called more simply the Intervention Testing Program, which began in the early 2000's to look at the potential for various interventions, including vitamins and pharmaceuticals and otherwise, to extend the lifespan of mice. While mice are much more genetically close to us, sharing 92% of their genome in common with us, and discoveries are thus far more likely to have eventual clinical applicability, the cost and time involved in screening are also geometrically more expensive. Herein lies the value of doing broad screening with lower organisms like C. elegans which can then potentially make its way up to mammal research and maybe, if we're very very lucky, clinical research in humans. The Role of Proteostasis in Aging Gordon talks about the role of proteostasis in the aging process. Proteostasis refers to homeostasis of all the proteins inside and outside of cells. New proteins are constantly being made inside cells and secreted outside of cells in order to perform the various functions of each cell whether it is a neuron or a heart cell. At the same time, older proteins are degraded so they can be replaced by new proteins. This relationship between the production of new proteins and the clearance of old proteins is known as proteostasis. When proteostasis becomes disrupted with age and this can lead to age-related aggregation of proteins which can then accelerate the aging process. Gordon's data, as discussed in this podcast, suggests there is a correlation between compounds that affect protein aggregation also affect lifespan. Heat Shock Increases Lifespan of C. elegans In a paper that Gordon published a little more than 2 decades ago, he showed that heat shocking worms could extend their lifespan by 15% and that this was dependent on heat shock proteins. He also found that repeated heat stress treatments had an even more robust effect. Heat shock is a prime example of hormetic stresswhich is a type of stress that in the right dose is slightly stressful to cells, elicits a biological stress response that has a cumulative effect that is otherwise a net gain in resilience that creates a benefit to the organism as a whole. Heat shock proteins (a.k.a. HSPs) help all other proteins maintain their proper 3-dimensional structure in the cell which is important for the specific function of each protein. The 3-dimensional is also very important for the normal half-life of a protein. Damage as a consequence of normal metabolism and immune function damages proteins and disrupts their structure and can lead to protein misfoldingthis can prevent a protein from being properly degraded which can lead to protein aggregation. Protein aggregation is associated with neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease and cardiovascular disease. Increased expression of heat shock proteins from heat exposure help repair proteins that have been damaged and this prevents protein aggregation. HSPs have also been shown to protect against neurodegenerative diseases. What is interesting is that in addition to heat stress increasing HSPs (to help prevent from misfolding) Gordon mentions that heat also activates autophagy...which makes sense you might want to clear away any damaged cells that have misfolded proteins accumulating in them that were not already sufficiently mitigated by HSPs. Plausible Human Relevance This research may also have relevance to humans. Heat shock proteins that are activated by heat and one study has that humans that use a 163F sauna for 30 minutes increased their heat shock protein levels 49% over baseline and these elevations persist for 48 hours. Other associative studies in humans have shown that using the sauna 2-3 times per week was associated with a 24% lower all-cause mortality and 4-7 times per week was associated with a 40% lower all-cause mortality. There was also a strong inverse association between sauna use and dementia and Alzheimer’s disease. Using the sauna 2-3 times per week was associated with a 20% lower Alzheimer’s risk and 4-7 times per week with a 66% lower risk of Alzheimer’s disease.

Kangen Water Burbank 05.11.2020

Kangen water is the single most important choice to make for health and longevity

Kangen Water Burbank 19.10.2020

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Kangen Water Burbank 24.09.2020

REPLAY! Chris Record teaching how beginners can create income online with their own e-commerce store! Join our 3-Day Ecommerce Mastermind this Weekend for only $100 at http://InternationalAffiliateConference.com

Kangen Water Burbank 11.09.2020

The drone photography is amazing. http://4plnk1.com/cbl.php?cbid=rr022727&f=2

Kangen Water Burbank 30.08.2020

Here are the top six things I have learned in my quest to reverse cancer without using drugs surgery or radiation

Kangen Water Burbank 24.08.2020

This is a phenomenal podcast. Dr. Tom Seyfried is one of the main voices out there on the subject of diet as a means to protect against and reverse cancer, diab...etes, Alzheimers epilepsy and more. http://metabolicoptimization.com//podca/75-thomas-seyfried. here are the show notes: This episode features cancer researcher Thomas Seyfried. Dr. Seyfried has constructed a new theory of cancer contending that cancer originates from metabolic dysfuction rather than genetic mutations. He summerized his theory in his 2012 book Cancer as a Metabolic Disease. His ideas may someday completely reconfigure cancer therapy as we know it -- for the better. In this episode you will learn: About the Somatic Mutation Theory of Cancer [8:00] The events that led Dr. Seyfried to believe that the consensus view of cancer was wrong [13:19] The discovery that ketogenic diets slow the growth of cancer in mice [13:19] The compelling series of nuclear transfer experiments that support the metabolic theory of cancer [18:20] (see explanation of experiments below) Mitochondrial transfer experiments provide evidence that cancer is driven by mitochondrial dysfunction [20:34] Why the theory of cancer matters so much [28:30] How, sadly, economics and personal incentives might be inhibiting progress [29:00] Good therapies will incite change [30:24] What is metabolic cancer therapy [34:45] The Press Pulse model of cancer therapy [38:15] Ketogenic cancer therapy clinical trials are difficult and need to be done cautiously [42:00] How far can we push the ketogenic diet; can blood glucose be brought to extremely low levels and ketones be supplemented to bring cancer cells to a metabolic tipping point [45:40] How the ketogenic diet can potentially make other cancer drugs and therapies more effective and less toxic [49:23] What would Dr. Seyfried do if he was diagnosed with a cancer that was nonresponsive to standard of care cancer therapy [51:20] Metabolic therapies to prevent recurrence [55.00] Metabolic therapies for cancer prevention [54:00] A new way to reign in health care spending while improving outcomes [59:25]

Kangen Water Burbank 13.08.2020

If you are in process of reversing a serious disease or are simply interested in having the highest level of health possible then drinking Kangen water daily is critical. Learn more at hollywoodkangen.com

Kangen Water Burbank 09.08.2020

Here is some of the latest info I've picked up on natural cancer reversal and hormone balancing. Hope it helps. LMK if you have anything you would like to know more about.

Kangen Water Burbank 21.07.2020

So you are telling me eating a whole food plant base diet is too expensive, looking at the picture you tell me what really is too expensive. Oh by the way those... of you that feel eating organic is too expensive for your budget be looking for my next video I will show you how you can afford it. EAT ORGANIC! Only you can make the choice start today or pay later which one of those two lifestyles would you like to live. Have a healthily day and be safe this Labor Day weekend. See more

Kangen Water Burbank 17.07.2020

Check out hollywoodkangen.com for more info. If you sign up for the free newsletter or ebook I can get in touch and answer any questions.