AAT Bioquest, Inc.

Registration is still open for our flow cytometry webinar! See you there! #science #laboratory #biotech #biology #research #skilldevelopment

The glycoprotein CD14 plays a key role as a co-receptor for several cell signaling pathways, and is a popular target for immunologists. Cells known to express CD14 surface markers include macrophages, monocytes, neutrophils, dendritic cells, Langerhans cells and granulocytes. Is CD14 involved in your research? #immunotherapy #research #biotech #drugdiscovery #science #immunity... https://www.aatbio.com//cd14-cluster-of-differentiation-14

The plasma membrane is a thin semi-permeable membrane that separates the interior of all cells from their extracellular environment. It is one of the most prominent fluorescent labeling targets because of its importance in cell health, behavior, and signaling. Is the cell membrane a feature in your work? https://www.aatbio.com//cell-structures-and-organelles-pla... #biotech #research #cellanalysis #biology

AAT Bioquest is hosting a complimentary webinar for those interested in improving their understanding and efficiency in lab: Fundamentals and Applications of Flow Cytometry. Registration is now open! #webinar #research #biotech #laboratory #science

Traditional Gram staining is an inexpensive but labor-intensive 5-step staining process. Modern techniques and all-inclusive kits are more efficient and may be suited to time-sensitive experiments or procedures requiring minimization of possible human error. https://www.aatbio.com/catalog/gram-staining #bacteria #fluorescence #biotech

Cell proliferation analysis is a very important aspect of drug development and investigation of other biological processes. How would you use these assays? https://www.aatbio.com/catalog/cell-cycle-and-proliferation #cellbiology #drugdevelopment #drugdiscovery

There are vast numbers of commercially-available assays on the market for most common experimental requirements, but for highly-specific or cutting-edge research, custom assays must still be developed and optimized. Given that not all laboratories have the resources to commit to this, assay development services are commonly used to build a novel or adapted test for specific needs. AAT Bioquest offers multiple services, including developing custom assays, for common and unusual requirements and methodologies. https://www.aatbio.com/services/assay-development #assaydevelopment #assays #research

Fluorescent derivatives of phalloidin have turned out to be enormously useful in localizing actin filaments in fixed cells and tissues, as well as, for visualizing individual actin filaments in vitro. Fluorescent phalloidin derivatives have been used as an important tool in the study of actin networks at high resolution. https://www.aatbio.com//cell-structures-and-organelles-f-a #science #actin #fluorescence #phalloidin

Similar to tyramide signal amplification (TSA), brighter PSA imaging uses the analyte-dependent reporter enzyme, horseradish peroxidase (HRP), to catalyze the covalent deposition and binding of labeled-Styramide substrates onto a target protein or nucleic acid sequence in situ. https://www.aatbio.com//power-styramide-signal-amplificati #enzymes #biotech

Fluorescein derivatives are one of the most commonly used fluorescent labels for biological detection in flow cytometry and immunofluorescence due to their high absorptivity, excellent fluorescence quantum yields and good water solubility. Do you use these classic options, or an alternative? https://www.aatbio.com/catalog/fluoresceins #fluorescence #biotech #science #laboratory

Among ROS, hydrogen peroxide is a major regulator and by-product in many signal transduction pathways. The cell-permeable OxiVision hydrogen peroxide sensors produce H2O2-selective fluorescence with minimal background. Explore the catalog of sensors and integrated kits for what will best integrate into your workflow. https://www.aatbio.com/catalog/oxivision-sensors #biotech #ROS

Immunohistochemistry (IHC) is a commonly used technique to monitor protein expression and localization in the context of tissue morphology. How do you apply this to your work? https://www.aatbio.com/catalog/immunohistochemistry-ihc #drugdiscovery #biotech #science #antibody

The endoplasmic reticulum is comprised of an interconnected network of flattened, membrane-enclosed sacs and tubules that extend from the nuclear membrane throughout the cytoplasm. Our Cell Navigator Live Cell Endoplasmic Reticulum Staining Kits selectively stain the ER and are available in many colors for use in multiparametric experiments. https://www.aatbio.com//cell-structures-and-organelles-end #organelles #cellbiology #biotech

Labeling an antibody with a specific tag has become an important and routine procedure in biological sciences and medical research. AAT Bioquest offers a comprehensive suite of antibody and protein labeling kits to choose from. Designed for the novice scientist in mind, these kits have the easiest protocols and require the least amount of hands-on experience. https://www.aatbio.com/catalog/antibody-and-protein-labeling #science #antibody #biotech

Cell viability often corresponds with cell health and the ability of a cell population to survive and function successfully. Our cell viability indicators and assays are designed to measure the different characteristics of cell viability and produce visual readouts of cell health using a microplate reader, fluorescence microscope or flow cytometer. https://www.aatbio.com/catalog/cell-viability #cellviability #biotech #science

The AAT Bioquest Von Hippel-Lindau disease tumor suppressor inhibitors (IC50, Ki) data table is an open-access resource for researchers. It includes the structure, compound name, and associated IC50 and Ki values of compounds known to inhibit the development and growth of the tumors caused by this disease. The table can be sorted in order of any of the columns, for user convenience. https://www.aatbio.com//von-hippel-lindau-disease-tumor-su #VHL #Cancer #Database #openaccess