That's Good Science

Need a better #singlecell #RNAseq method to discover novel and rare #biomarkers? We can help. Join us for a session of our live webinar series on the capabilities of our ICELL8 cx automation system. Learn about our full-length scRNA-seq solution and its ability to detect novel insights from single cells and nuclei. Review the live webinar schedule and register now: http://ow.ly/Nm0S50JenpW

Need a solution for going from sample to data analysis for TCR-seq in the rhesus macaque? Visit John Beckford, PhD, at his poster today if you’re attending The Antibody Society's Adaptive Immune Receptor Repertoire (AIRR) Community Meeting in La Jolla, CA. Details: http://ow.ly/TSaY50Jcwkb #AIRRC6 #TCRseq #immuneprofiling #immunerepertoire

ICYMI: Neutrophils split into different types and migrate to organs to induce antigen-specific T-cell responses. This basic research study by Mauro Di Pilato, Santiago F. Gonzalez, and colleagues used in vivo imaging of viral infection in mice, flow cytometry, and RNA sequencing and analysis. These methods uncovered insights into the effect of neutrophil type on T-cell induction. Using these insights, the authors were able alter neutrophil migration and augment HIV-specific T...-cell responses to HIV antigens delivered by a poxvirus, vaccinia virus (VACV) vector. These insights into immune response mechanisms could offer alternative strategies for vaccine vector design for prevention of HIV and other viral infections. Read the article in npj Vaccines: https://doi.org/10.1038/s41541-021-00314-7 #ThrowbackTGSThursday #AdaptiveImmunity #InnateImmunity #vaccine #neutrophils #immunology

Need a better BCR-seq method that captures all the heavy and light chain isotypes? Visit Bryan Bell, PhD at his poster today if you’re attending the Antibody Society's Adaptive Immune Receptor Repertoire (AIRR) Community Meeting. Details: http://ow.ly/i6IR50Jbsyl #AIRRC6 #BCRseq #immuneprofiling #immunerepertoire

Come chat about all things immune receptor profilingor NGS in generalwith Bryan Bell, PhD, here at our booth at the Antibody Society's Adaptive Immune Receptor Repertoire (AIRR) Community Meeting in La Jolla, CA. Details: http://ow.ly/B8bm50Jar1O #AIRRC6 #TCRseq #BCRseq #immuneprofiling #immunerepertoire

Hot off the press Takara Bio has updated our trusted SMART-Seq cDNA kits to include an easy, two-step enzymatic fragmentation library prep kit. Get the complete solutionfrom cDNA synthesis to sequencing-ready libraryall from the same source! Learn more: http://ow.ly/99ed50DqCLb

This #ThatsGoodScience Thursday, we are cheering on Korukluoglu et al. for creating a rapid SARS-CoV-2 detection assay and quickly sharing it with the world. Fast SARS-CoV-2 variant detection is a crucial part of COVID-19 surveillance, and assays that accurately detect existing and new variants help us understand viral propagation. Scientists from the World Health Organization (WHO) and from Bioeksen R&D Technologies Ltd. developed a 40-minute RT-qPCR assay to simultaneousl...y screen for both B.1.1.7 and B.1.351 variants, discovered in the UK and South Africa, respectively. Not only is it quick, but their variant detection fully agreed with NGS and Sanger sequencing results on over 1,000 patient samples. Check out the paper and related information here: http://ow.ly/vPC150Dx4tI #sarscov2 #rtpcr #b117 #b1351 #covid19 #variants #variant #N501Y

Have you ever felt overwhelmed by the landscape of TCR-seq methods available? Well worry no more; we’ve got a helpful blog for you! A new study from Dr. Encarnita Mariotti-Ferrandiz in Nature Biotechnology breaks down popular TCR-seq methods based on reproducibility, replicability, sensitivity, and specificity to help you narrow down to the best method. ... Read more here: http://ow.ly/UBvI50C6vqq #natureresearch #newresearch #scienceblog