Jean Marc Sobczyk, MD, ND

Thank you! I am very grateful that more than 6000 people found my page worthy and decided to follow me. In return, for a limited time (until Feb 15th).... I want to offer you a $50 discount on all 30 min appointments (new patients or follow-ups). The same discount will be applied to a longer appointment if needed. All you need to do is to schedule your visit using the link available in my bio and type IG50OFF in the comment section All the calls via Zoom are encrypted to make your appointment safe and confidential. Alternatively, you can DM me, call or email me. See you soon With gratitude, Dr. Jean-Marc Sobczyk, Precision medicine and Genomics. #mthfr #fertility #healthypregnancy #mthfrgene #drjeanmarc #mthfr_expert #mthfrawareness #genomics #nutrogenomics #methylation #detox #biohacking #optimalhealth #infertility #hellomthfr #epigenetics

HIGH or LOW Methylfolate: A QUICK REVIEW Follow @mthfr_expert, @drjeanmarc LOW 5-MTHF (methylfolate) may be lacking in association with insufficient dietary folate intake (abundant in dark green leafy vegetables). ... It can also be low in alcoholism, malabsorption, inherited single nucleotide polymorphisms (SNPs), variations in folate cycle enzymes (e.g., MTHFR ) gastrointestinal folate transporter. Methotrexate and some anticonvulsant medications may also reduce methylfolate. Deficiency is associated with megaloblastic anemia and appears to be associated with CVD, cancers, impaired cognitive function, neurological development, and detoxification. HIGH levels of 5-MTHF may be associated with excessive supplementation or compromised activity of MTR (genetic variations, B-12 and/or zinc insufficiency, supplemental SAMe, excessive levels of nitric oxide, lead, mercury, acetyl aldehyde (from candida overgrowth), and inflammation) and MTRR. HIGH Methylfolate levels can cause symptoms that include but are not limited to irritability, severe anxiety, insomnia, achy joints, rash. #mthfr #mthfrgenemutation #mthfrawareness #genomics #epigenetics #healthybrain #depression #treatdepressionnaturally #mthfrSNPS #mthfrgene #infertility #fertility #mthfr_expert #DrJeanMarc Credits: Doctor's Data

Just got your labs back from your doctor? Test for MTHFR mutations if you find these on your blood test results Follow @mthfr_expert @drjeanmarc Check your labs to see if you have any of these.... 1- Increased MCV above 90 2- Chronically low WBC, neutrophils and lymphocytes count 3- Vitamin B12 below 500 4- Elevated homocysteine level above 9 5- Low hemoglobin 6- Elevated GGT 7- Elevated or Low cholesterol 8- Low or High blood pressure 9- Low Thyroid function FT4 (Free T4) 10- Low fat-soluble vitamins levels include Vitamins A D E K If you want to test for MTHFR, ask your doctor to write an order. If your doctor refuses, I have an option for you to check in my bio. You can always DM me if you have any questions or want to discuss a more complicated case. #mthfr #mthfrgenemutation #mthfrawareness #genomics #epigenetics #healthybrain #depression #treatdepressionnaturally #mthfrSNPS #mthfrgene #infertility #fertility #mthfr_expert #DrJeanMarc

TYLENOL (Acetaminophen) and MTHFR: A BAD COMBINATION Follow @mthfr_expert and @drjeanmarc Cyt 3A4 and Cyt 2E1 (which are part of the Cyt P 450 family) are the two primary enzymes in our liver breaking down Tylenol. Tylenol metabolism starts in the liver during the Phase 1 detox. The byproduct resulting from this first step is even more toxic and can damage your liver if not adequately taken care of in Phase 2. ... Phase 2 detoxification processes use Glutathione to diminish its toxicity before being eliminated. 4000 mg is considered the maximum safe daily dose of Tylenol/Acetaminophen an individual can take. If you take a higher dose OR if your body is deficient in Glutathione, then the toxic byproduct NAPQI [N-acetyl-p-benzoquinone imine] made after phase 1 starts to accumulate and irritate and destroy the liver cells. An individual with an MTHFR mutation has trouble producing Glutathione and may quickly become deficient. It is estimated that taking the maximum daily dose of Tylenol depletes our Glutathione entirely for 24 hours. Let’s think one second about individuals with chronic pain taking daily a high dose of Tylenol. You then realize that they are always running low on Glutathione and cannot detoxify anything else (environmental toxins we are exposed 24/7, viruses and bacteria, pesticides, etc.). Interestingly, the antidote to acetaminophen overdose is N-acetylcysteine [NAC]. NAC is a precursor of Glutathione and may prevent liver damage created by the medication. To stay on the safe side, every individual with an MTHFR mutation can potentially damage the liver by taking a dose of Tylenol, increasing oxidative stress, free radicals, Cell and DNA damage, and should stay away from Acetominophen. #saynotoTylenol #acetominophen #livertoxicity #NAC #glutathione #mthfr #mthfrawareness #liverhealth #genes #epigenetics #nutrigenomics #painkillers #nopain #detoxification #liverdetox #mthfrandpain @drjeanmarc @mthfr_expert #drjeanmarc #mthfr_expert See more

Do you believe in the one size fits all approach for MTHFR? Let me know what you think! Follow @mthfr_expert, @drjeanmarc. ... Regarding MTHFR and genetic testing, the one size fits all approach is not working because of the too many variables you must consider. Everyone is unique with their own set of genetic traits and genetic mutations. How can we let the software tell us what supplements are good for us based on an algorithm? While it may work for the majority, I also have noticed that some individuals do not react well to methylated folate and b12. They have an MTHFR mutation, so they should benefit from methylated vitamins but don’t. The software does not consider what makes us different, our dietary habits, our daily stress exposure, our environmental exposure to toxins through food, air, and water, how much we exercise, etc. This is why you should not trust companies telling you what to take only based on your test results. Consider instead seeing a doctor, a physician trained to consider all the factors, with a strong background in biochemistry, a doctor trained in nutrigenomics and epigenetics, and not a computer that only reads your raw data file to extrapolate a plan that may work for you. If it makes sense to you, then I am here to help. I do not treat lab results; I help real people with real health concerns, not just numbers on a piece of paper, whether it is a genetic report or standard blood work. I offer a FREE 10 min discovery visit; book now! (link in my bio/profile) Follow @mthfr_expert @drjeanmarc #mthfr #epigenetics #mthfrawareness #nutrigenomics #mthfrreport #23andme #genetictesting #genes #geneticmutations #mthfr677 #akashacenter #drjeanmarc #mthfr_expert #biohacker #biohacking #optimalhealth #fertility #Healthypregnancy See more

Best Foods For MTHFR METHYLATION supporters (MTHFR mutations) Folates food sources: dark leafy greens and lentils, garbanzo beans, Asparagus, Spinach, lima beans, Vitamin B12 food sources: Animal products: Clams, Mussels, Beef, Turkey... Zinc food sources: (zinc helps process methyl folate): Brazil nuts, Pine nuts, Cashews, sunflower seeds, Pecans, Almonds and Beans, Oysters METHYLATION offenders Folic acid (cheap supplements, lower quality supplements) contains this synthetic folate, challenging to process, and that interferes with natural folate conversion into methyl folate. Folic acid is found in processed food and fortified (enriched food): rice, pasta, cereals, white flour, bread (look at the label) METHYLATION poisoners Alcohol Any Heavy metals: mercury (fish high in mercury are large fish (shark, tuna), lead, arsenic METHYLATION BOOSTERS Water 1/2 the body weight in Oz of water and more during summer and when exercising Electrolytes (sodium, potassium, magnesium, calcium) usually found in powder form or packets at healthy foods stores METHYLATION LEFTOVERS Choline and Betaine rich food (especially if you have a PEMT mutation)- Betaine rich foods: Beets, Spinach, Quinoa, Sweet potato, brown rice, wheat bran, rye bran Choline rich foods: Eggs, Liver, Spinach, Beets, Shellfish, Kale, Wheat germ grass, Brussel sprouts, Broccoli LET'S WRAP THIS UP Eating well to boost methylation is so easy to do. Just Go to the grocery store, avoid the aisle in the middle, Focus on the fresh food section, There you have it; you should be able to find everything on that list. Bonus, you may even find that it costs less, nutritious, healthy food cost less than you think! And make you healthy! Want to know more about improving methylation, optimizing your health, and unlock your TRUE potential? Click here to book your FREE discovery one to one phone call with Dr. Jean-Marc Sobczyk (Your methylation and MTHFR consultant) #MTHFR #MthfrAwareness #mthfrDiet #mthfrmutation #mthfrgene #epigenetics #genomics #Biohacking #optimalhealth #unlockyourgenes #mthfr_expert #drjeanmarc See more