Crinetics Pharmaceuticals

Congenital #hyperinsulinism is tough to diagnose, but considering the majority of patients with congenital HI end up with a developmental delay or defect, timely recognition, diagnosis and treatment are crucial. Learn the signs of this #raredisease

Founded in endocrine research, Crinetics is committed to developing treatments that have a positive impact on the lives of #raredisease patients. Paltusotine, our investigational drug for #acromegaly, is starting Phase 3 clinical trials, and that’s just one example of the important work we're doing to combat endocrine disease.

Crinetics is pleased to announce that our company’s oral ACTH antagonist for the treatment of Cushing’s disease and Congenital Adrenal Hyperplasia (CAH), has advanced into Phase I study. This treatment has the potential to offer patients with Cushing’s disease, CAH, and related diseases a life-saving treatment option. #RareDisease

Crinetics is proud to partner with Pituitary World News for the Second Annual Virtual Patient Gathering Saturday, Feb. 6, 2021 - Noon to 3pm EST ( 9am-Noon PST) For More Info: http://bit.ly/2YEvpwP

Crinetics announced that the #FDA has granted rare pediatric disease designation (RPD) for CRN04777, an sst5 agonist being developed for congenital #hyperinsulinism. Congenital HI is a devastating #raredisease in which infants are born with life threatening hypoglycemia due to excess insulin secretion. A Phase 1 clinical study of CRN04777 is planned for in early 2021. Read more here: https://crinetics.com/crinetics-pharmaceuticals-receives-r/ Under the FDA’s Rare Pediatric Disease Priority Review Voucher Program, companies may be eligible to receive a priority review voucher following approval of a product with an RPD designation. #pediatrics #hypoglycemia #insulin

We are pleased to welcome Adriana to the executive team to lead our Human Resource function." - Scott Struthers, Ph.D., Founder and Chief Executive Officer of Crinetics

Every year at Crinetics, we take a company photo, a moment in time when we are all together (with our pups). This year, of course, we’ve spent much of the spring apart, but we wanted to show that now more than ever we’re still together, working for our patients every day.

Support Groups vs Self Help Groups - Navigate the difference

In Faces of Acromegaly, courtesy of Acromegaly Community, 23 people living with acromegaly share their before and after photos and share some insight on living with the Acromegaly: from symptoms to treatment, to messages of hope.

Crinetics Pharmaceuticals reports positive interim results for the Acrobat Edge Phase 2 Trial of Paltusotine (CRN00808) In Acromegaly Patients

Cushing’s disease results from a pituitary tumor that oversecretes the hormone ACTH, which in turn causes over-secretion of cortisol. Cortisol is the body’s main stress hormone. The effects of having too much cortisol include getting excess fat deposits in the collarbone, back of neck, face, and trunk, excessive sweating, thinning of the skin, muscle weakness, extra hair growth, depression/anxiety, high blood pressure, osteoporosis, high blood sugar, and heart disease. Untreated, it can lead to an early death.

Sending Special Thanks To Acromegaly Community

It was great to have students from Miramar College Chemistry Club visit us last Friday. We love seeing the future of science.

2nd Podcast in this Great New Series - gives an unfettered look at efforts to develop new drugs to solve unmet needs in acromegaly, Cushing’s and rare neuroendocrine diseases.

We are honored to be part of Pituitary World News brand new podcast series

It’s a great thing when our work brings us to Philadelphia to support this wonderful organization, CHI Congenital Hyperinsulinism International at their annual Sugar Soiree benefit. Generous donations from this event allow CHI to continue to raise awareness to increase timely diagnosis, provide educational opportunities, support HI families and help them access the care they need, and support research. It really is the #SweetestCause

Crinetics showing our support for Acromegaly Awareness Day Big thanks to Jill Sisco, President of Acromegaly Community for joining us!