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Where to get COVID-19 test? Enter your zip code to find out the nearest COVID-19 test site. (from US HRSA.gov website) https://findahealthcenter.hrsa.gov/ 1. Go to clinics instead of crowded large facilities. 2. Fees: Testing and Treatments are free. ... If confirmed, home isolation for 14 days, please help stop spreading COVID-19. Proactive screening to stop the spreads.

CDC Updates Flu Vaccine recommendations for 2019 - 2020 season.... (CDC)CDC has released its recommendations for influenza vaccination for the 2019-2020 season. Routine annual influenza vaccination continues to be recommended for all people 6 mo of age who don’t have contraindications. No preference is given to any one vaccine product when multiple products may be appropriate. Among the changes this year:... -> Afluria Quadrivalent, previously licensed for individuals 5 yo, is now recommended in children 6 mo. The dose volume is 0.25 mL per dose in children ages 6-35 mo, and 0.5 mL per dose for those 36 mo. -> Fluzone Quadrivalent can now be dosed at either 0.25 mL or 0.5 mL per dose in children 6-35 mo. Those 36 mo should receive 0.5 mL per dose. More info is available in the MMWR article PDF. Related Resource: CDC Influenza Vaccination 2019-20 | Epocrates Guideline Synopsis

Risk for Dementia May Increase With Long-Term Use of Certain Medicines https://jamanetwork.com//jamainternalm/fullarticle/2736353 A new study suggests that people who take a class of common medicines called anticholinergic drugs for several years may be more likely to develop dementia as they age.... This is not a new hypothesis about these drugs, which are used to treat a wide range of conditions from depression to epilepsy to incontinence. But the study, published in the journal JAMA Internal Medicine, is large, and it analyzed the use of the medications in more detail and over a longer period of time than many previous studies. Here’s what is known about the potential link between anticholinergic medicines and dementia: Which drugs are we talking about? Anticholinergic drugs include the antipsychotic clozapine; the bladder drug darifenacin (marketed as Enablex); the anti-nausea drug scopolamine; the bronchodilator ipratropium; the muscle relaxant tizanidine; antihistamines such as diphenhydramine (brand names include Benadryl), and antidepressants such as paroxetine (brand names include Paxil). These medications work by blocking a chemical called acetylcholine, which acts as a neurotransmitter and is involved in many nervous system functions including muscle movements, heart rate, the widening of blood vessels, respiratory functions and muscle contractions in the stomach during digestion. For more info, call CrePlus Drugs @ 559-385-7413

FDA adds Boxed Warning for increased risk of death with gout medicine Uloric (febuxostat) The U.S. Food and Drug Administration (FDA) has concluded there is an increased risk of death with Uloric (febuxostat) compared to another gout medicine, allopurinol. This conclusion is based on our in-depth review of results from a safety clinical trial that found an increased risk of heart-related death and death from all causes with Uloric. Uloric was FDA-approved in 2009 to treat a t...ype of arthritis called gout in adults. Gout happens when a naturally occurring substance in the body called uric acid builds up and causes sudden attacks of redness, swelling, and pain in one or more joints. Uloric works by lowering uric acid levels in the blood. When Uloric was approved in 2009, it was included in Warning and Precaution regarding possible cardiovascular events in patients treated with Uloric in the current prescribing information and required the drug manufacturer, Takeda Pharmaceuticals, to conduct a large postmarket safety clinical trial. The trial was conducted in more than 6,000 patients with gout treated with either Uloric or allopurinol. The results showed that overall, Uloric did not increase the risk of these combined events compared to allopurinol. However, when the outcomes were evaluated separately, Uloric showed an increased risk of heart-related deaths and death from all causes. In patients treated with Uloric, 15 deaths from heart-related causes were observed for every 1,000 patients treated for a year compared to 11 deaths from heart-related causes per 1,000 patients treated with allopurinol for a year. In addition, there were 26 deaths from any cause per 1,000 patients treated for a year with Uloric compared to 22 deaths per 1,000 patients treated for a year with allopurinol. Patients should tell their health care professional if they have a history of heart problems or stroke and discuss the benefits and risks of using Uloric to treat their gout. Seek emergency medical attention right away if you experience the following symptoms while taking Uloric: -Chest pain -Shortness of breath -Rapid or irregular heartbeat -Numbness or weakness on one side of your body -Dizziness -Trouble talking -Sudden severe headache... https://www.fda.gov/Drugs/DrugSafety/ucm631182.htm Call CarePlus Drugs to get more information at 559-385-7413..

New Preventive Options for Migraine Headache- The American Headache Society encourages greater use of preventive tx. Some key recommendations from a recent consensus statement include: -Offer an agent w/ established efficacy: divalproex sodium, valproate sodium, topiramate, metoprolol, propranolol, timolol, frovatriptan, onabotulinumtoxinA.... -Start low and titrate slowly for oral agents; continue trial for at least 8wk at target or usual effective dose. If partial response, advise that cumulative benefits may be seen at 6-12mo; consider combining preventive drugs from different classes. -Monoclonal antibodies erenumab, fremanezumab, and galcanezumab are injected SC on a schedule of weeks, and may be combined w/ PO preventive tx in adults. -Cognitive behavioral therapy, biofeedback, and relaxation tx may be used alone or in combo w/ pharmacotherapy.... For more information , call CarePlus Drugs @ 559-385-7413 and talk to our Pharmacist for more info.....

How dehydration and overhydration affect your body and brain:

Questions Answered: Latent TB infection & TB Diseae: Not everyone infected with TB bacteria becomes sick. As a result, two TB-related conditions exist: latent TB infection and TB disease.... Latent TB Infection: TB bacteria can live in the body without making you sick. This is called latent TB infection. In most people who breathe in TB bacteria and become infected, the body is able to fight the bacteria to stop them from growing. People with latent TB infection: Have no symptoms Don’t feel sick Can’t spread TB bacteria to others Usually have a positive TB skin test reaction or positive TB blood test May develop TB disease if they do not receive treatment for latent TB infection Many people who have latent TB infection never develop TB disease. In these people, the TB bacteria remain inactive for a lifetime without causing disease. But in other people, especially people who have a weak immune system, the bacteria become active, multiply, and cause TB disease. TB Disease: TB bacteria become active if the immune system can’t stop them from growing. When TB bacteria are active (multiplying in your body), this is called TB disease. People with TB disease are sick. They may also be able to spread the bacteria to people they spend time with every day. Many people who have latent TB infection never develop TB disease. Some people develop TB disease soon after becoming infected (within weeks) before their immune system can fight the TB bacteria. Other people may get sick years later when their immune system becomes weak for another reason. For people whose immune systems are weak, especially those with HIV infection, the risk of developing TB disease is much higher than for people with normal immune systems. The Difference between person infected with Latent TB Infection (LTBI) and TB Disease: LTBI: -Has no symptoms -Does not feel sick. -Can not spread TB bacteria to others. -Usualy have normal chest X-Ray and negative sputum smear. - My need treatment for Latent TB infection to become TB disease. TB: -Has symptoms that may include --a bad cough that lasts 3 weeks or longer --pain in the chest --coughing up blood or sputum --weakness or fatigue --weight loss --no appetite --chills --fever --sweating at night Usually feels sick May spread TB bacteria to others Usually has a skin test or blood test result indicating TB infection May have an abnormal chest x-ray, or positive sputum smear or culture Needs treatment to treat TB disease..

Questions Answered. Here are some updates on some of the new drugs approved in the month of July: Jynarque (tolvaptan): ... New oral drug for autosomal dominant polycystic kidney dz Lumify (brimonidine ophthalmic): New OTC eye drop for relief of ocular redness Olumiant (baricitinib): New oral drug for moderate to severe rheumatoid arthritis Tavalisse (fostamatinib): New oral drug for chronic immune thrombocytopenia Xepi (ozenoxacin topical): New cream for impetigo Call CarePlus Drugs to get more info @ 559-385-7413.